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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding) for a Specific Protein or Metabolite

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of a specific protein or metabolite in your blood using a dye-binding method with bromocresol green. It may be used to assess certain metabolic or functional conditions.

Quick summary

["This test helps evaluate protein or biochemical levels that may indicate underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86157-5
Short code
S pneum Da 8 IgG 2:1 Ser-Rto
Synonyms
S pneum Da 8 IgG 2:1 Ser-Rto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol green (BCG) method detects the binding capacity of a protein or substance in your blood. When BCG dye binds to the analyte, its color changes, allowing for measurement of concentration. This test is often used to quantify proteins like albumin or other metabolites that interact with the dye.

Why It Might Be Ordered

Your healthcare provider may order this test to monitor conditions affecting protein metabolism, kidney function, or other biochemical pathways. It could also be part of a broader evaluation for liver disease, nutritional deficiencies, or other metabolic disorders.

Sample Collection and Preparation

A blood sample is typically collected from a vein in your arm. The sample is processed into either serum (after clotting) or plasma (using an anticoagulant). The test measures the concentration of the analyte in this blood sample using the BCG dye method.

What to Expect Before the Test

No special preparation is usually required, but you may be asked to fast for 8–12 hours before the test if instructed by your provider. Avoiding certain medications or foods that could interfere with results may also be advised.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein/Dye Binding Test

Frequently asked questions

How might this test result affect my care?
Results may indicate abnormal protein or metabolite levels, which could signal conditions such as liver disease, kidney dysfunction, or nutritional deficiencies. Your provider will interpret the results in the context of your overall health and symptoms. Low or high levels may prompt further testing or adjustments to treatment.
What does a low result mean?
A low result could suggest conditions like malnutrition, liver disease, or kidney problems, where protein or metabolite levels are reduced. Your provider will discuss this with you based on your medical history and symptoms.
How often should I get this test?
Frequency depends on your health status and treatment plan. Your provider will determine how often this test is needed, whether it’s part of routine monitoring or for specific symptoms or conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy