Serum or plasma concentration of pneumococcal polysaccharide (19-valent) antibodies

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’ve received the pneumococcal vaccine (such as Prevnar 13 or Pneumovax 23) and want to check if your body produced enough antibodies to protect against pneumococcal infections. It may also be used in people with weakened immune systems, those with certain medical conditions, or those who have had recent pneumococcal infections.

What to Expect Before the Test

No special preparation is needed for this test. A blood sample will be drawn from a vein, usually in your arm. The process is quick and typically painless. If you’re on blood-thinning medication or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

Results are interpreted by your healthcare provider based on your medical history, vaccination status, and overall health. Low antibody levels may indicate an inadequate immune response to vaccination or a weakened immune system. High levels suggest a strong immune response.

Common Reasons for Testing

This test is often used to evaluate the effectiveness of pneumococcal vaccination, monitor immune function in high-risk individuals, or diagnose recurrent infections caused by pneumococcal bacteria.