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Serum or plasma mass concentration of immunoglobulin G (IgG) antibodies against pneumococcal polysaccharides (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures whether your body has produced antibodies against certain types of pneumococcal bacteria, which can cause serious infections like pneumonia, bloodstream infections, or meningitis.

Quick summary

["A positive result may help identify if your immune system is responding to pneumococcal exposure, but it’s not a direct measure of current infection risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86147-6
Short code
S pneum Da 8 IgG Ser-mCnc
Synonyms
S pneum Da 8 IgG Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects the presence of IgG antibodies specific to pneumococcal polysaccharides, which are sugar molecules found on the surface of some pneumococcal bacteria. These antibodies are part of your immune response to past exposure or vaccination. The test is qualitative, meaning it only tells you if antibodies are present rather than how much is present.

How the Test Works

Blood is drawn and processed to separate serum or plasma. The sample is then analyzed using an immunoassay method (likely clia or fia) to identify IgG antibodies against pneumococcal antigens. This helps determine if your immune system has recognized these bacteria before.

Why It Might Be Ordered

A healthcare provider may order this test if you have a history of pneumococcal infections, are at high risk (e.g., due to weakened immune systems, chronic conditions, or age), or if you’re being evaluated for immune response after vaccination.

What the Results Mean

A positive result indicates the presence of IgG antibodies against pneumococcal polysaccharides, suggesting your immune system has encountered these bacteria before. However, this does not confirm current infection or immunity. A negative result means no detectable antibodies were found.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Pneumococcal (Screen)

Frequently asked questions

What does a positive result mean?
A positive result means your immune system has likely encountered pneumococcal bacteria before, producing IgG antibodies in response. This could indicate past infection, vaccination, or both. However, it does not guarantee protection against future infections.
Can this test detect current pneumococcal infection?
No, this test only measures antibodies against pneumococcal polysaccharides and does not detect active infection. If you suspect a current infection, other tests or clinical symptoms would be needed.
Is this test the same as a pneumococcal vaccine antibody test?
Yes, this test is similar to measuring antibody levels after vaccination, but it focuses on detecting IgG antibodies against pneumococcal polysaccharides rather than specific vaccine components. Results may vary depending on the type of pneumococcal vaccine received.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy