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Serum or Plasma Protein Electrophoresis (Qualitative) with Bromocresol Green Staining

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood using a dye called bromocresol green. It helps identify abnormal protein patterns that may signal conditions like multiple myeloma, lymphoma, or other blood disorders.

Quick summary

["This test helps doctors check for unusual protein levels that could indicate serious blood diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47508-7
Short code
S pneum Da 9V IgG 2:1 Ser-Rto
Synonyms
S pneum Da 9V IgG 2:1 Ser-Rto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol green dye binds to specific protein groups in your blood, separating them into bands based on size and charge. This qualitative method helps visualize the relative amounts of albumin, globulins, and other proteins, which can be useful for detecting abnormalities in protein composition.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, or swollen lymph nodes. It’s also used to monitor conditions like multiple myeloma, lymphoma, or other disorders affecting protein levels in the blood.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma, which is tested with bromocresol green dye. The results are interpreted as qualitative bands rather than precise measurements.

Interpreting Results

Results are presented as distinct bands (e.g., albumin, alpha, beta, gamma globulins) that show relative protein concentrations. Abnormal patterns may indicate conditions like monoclonal gammopathy, infections, or inflammatory diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily qualitative and used for detecting abnormal protein profiles that may signal underlying diseases. While not a diagnostic test on its own, it can guide further testing (e.g., immunofixation electrophoresis) for conditions like multiple myeloma or plasma cell disorders. Results should always be reviewed by a healthcare professional in the context of your symptoms and medical history.

Short name

Bromocresol Green Protein Electrophoresis

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may show unusual protein bands or patterns, which could indicate conditions such as multiple myeloma, lymphoma, or other blood disorders. These findings require further evaluation by your doctor to determine the next steps, such as additional tests or treatments.
How long does it take to get results?
Results from this test are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink anything before this test?
No special preparation is needed for this test. You can eat and drink normally before your blood draw, as it does not affect the accuracy of the results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy