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Pneumococcal Nucleic Acid Detection (Serum/Plasma Probe)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Streptococcus pneumoniae* (pneumococcus) in your blood or plasma using a specialized molecular probe.

Quick summary

["Helps identify if bacteria are present before symptoms appear."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105437-8
Short code
S pneum DNA Nph Ql NAA+probe
Synonyms
S pneum DNA Nph Ql NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a molecular probe to detect genetic fragments of *Streptococcus pneumoniae* (pneumococcus), a common cause of pneumonia, meningitis, or bloodstream infections. It’s not a traditional antibody test but identifies the bacteria’s DNA directly, which can occur even before symptoms develop.

Why It’s Done

Your healthcare provider may order this test if you have signs of infection (e.g., fever, confusion, or respiratory symptoms) or if you’re at high risk for pneumococcal infections (e.g., young children, elderly adults, or those with weakened immune systems).

Sample Collection

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate plasma (the liquid part) for testing. This is a quick, non-invasive procedure.

What to Expect

You may feel slight discomfort at the injection site, but the procedure takes only a few minutes. No special preparation is needed, though you might want to drink water afterward to help reduce any bruising.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How soon will I get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will discuss them with you during a follow-up visit.
Can I eat or drink before this test?
No special diet is required, but avoid heavy meals or alcohol before your blood draw to minimize discomfort. Drink water as usual unless instructed otherwise.
Is this test covered by insurance?
Most insurance plans cover this test if ordered by a healthcare provider for medically necessary reasons. Check with your insurer for specifics, as coverage may vary.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy