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Pneumococcal Nucleic Acid Detection in Respiratory Specimen (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Streptococcus pneumoniae* (pneumococcus) in your respiratory secretions, such as sputum or nasal swab samples.

Quick summary

["Helps diagnose pneumonia or other infections caused by pneumococcus quickly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49672-9
Short code
S pneum DNA Spec Ql NAA+probe
Synonyms
S pneum DNA Spec Ql NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects genetic material (nucleic acids) from *Streptococcus pneumoniae*, a common cause of pneumonia, ear infections, and sinus infections. It does not measure the bacteria’s activity or count, but confirms its presence in your sample.

How the Test Works

A small sample of your respiratory secretions (e.g., sputum or nasal swab) is analyzed using a molecular technique (nucleic acid amplification probe). If pneumococcal DNA is found, the test result will indicate a positive result.

When You Might Need This Test

Your healthcare provider may order this test if you have symptoms like fever, cough, chest pain, or difficulty breathing, especially if you’ve been exposed to someone with pneumonia or have risk factors (e.g., weakened immune system, chronic lung disease).

What to Expect Before the Test

No special preparation is needed. You may expect to provide a sputum sample (coughing into a container) or a nasal swab. If you’re unsure, ask your provider how to collect the sample correctly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal NA Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times.
What does a positive result mean?
A positive result means your sample contained genetic material from *Streptococcus pneumoniae*, which may indicate an active infection. Your doctor will discuss next steps, such as starting antibiotics.
Can I have this test if I’m allergic to antibiotics?
Yes, this test is used to identify the infection, not to prescribe antibiotics. Your doctor will consider your allergy when deciding on treatment options.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy