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Pneumococcal Nucleic Acid Detection in Respiratory Specimen (Qualitative Probe-Based Assay)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your respiratory secretions, such as sputum or nasal swabs. It helps identify if you may have an infection caused by this bacterium.

Quick summary

["Quickly determines if pneumococcal bacteria could be the cause of your respiratory symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5035-1
Short code
S pneum rRNA Spec Ql Probe
Synonyms
S pneum rRNA Spec Ql Probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific genetic sequences unique to *Streptococcus pneumoniae*. These sequences are found in the bacteria’s DNA and are not present in human cells. The probe-based method amplifies and identifies these sequences to confirm infection.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like cough, fever, or difficulty breathing, especially if they suspect pneumonia or another respiratory infection caused by pneumococcus.

How It’s Performed

A sample of your respiratory secretions (e.g., sputum, nasal swab, or throat swab) is collected and sent to the lab. The test uses a molecular probe to detect pneumococcal genetic material directly from the sample.

What to Expect Before or After

No special preparation is needed. If you’re having a nasal or throat swab, you may experience mild discomfort. Results are typically available within 24 hours and can guide further treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal NA Test

Frequently asked questions

This test helps confirm a pneumococcal infection quickly, allowing for targeted antibiotic treatment if needed. Early identification can reduce complications and improve recovery.
Yes, this test is highly sensitive and specific for detecting pneumococcal bacteria. It can help rule out or confirm infections that may require antibiotics.
This test only detects the presence of pneumococcal genetic material, not the full bacterial load or other types of bacteria. It does not measure viral infections.
If you have symptoms like fever, chills, or worsening breathing, inform your provider if results are pending. This test is not used for routine screening but for suspected infections.
The specimen must be collected properly (e.g., deep nasal swab or sputum sample) to ensure accurate results. If the sample is contaminated or improperly handled, results may be unreliable.
Antibiotics may be prescribed based on test results, but your provider will consider other factors like allergies, history, and symptoms before choosing treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy