Serum or Plasma Protein Electrophoresis with Bromocresol Green (BCG) Dye Binding Assay
This test measures the distribution of different protein types in your blood, often used to check for conditions affecting protein balance, such as kidney disease or certain cancers.
["This test helps identify abnormal protein patterns that may signal underlying health issues."]
Key facts at a glance
- LOINC
- 92947-1
- Short code
- S pyo DNA BAL NAA+non-prb-NCncRng
- Synonyms
- S pyo DNA BAL NAA+non-prb-NCncRng
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- non-probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Protein electrophoresis separates blood proteins into fractions (e.g., albumin, globulins) based on size and charge. The BCG dye binding assay quantifies protein concentration in each fraction. This helps detect conditions like multiple myeloma, liver disease, or kidney disorders that alter protein levels.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if lab results suggest abnormal protein levels. It’s also used as part of routine monitoring for certain chronic conditions.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma for testing. The BCG dye assay measures protein concentrations in each fraction, providing a detailed profile of your blood proteins.
Possible Results and Interpretation
Results show protein distribution across fractions. Abnormal patterns (e.g., high or low levels in specific fractions) may indicate conditions like protein-losing syndromes, infections, or metabolic disorders. Your provider will discuss findings with you.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for diagnosing and monitoring conditions affecting protein metabolism. For example, elevated globulin levels may signal chronic inflammation or autoimmune diseases, while abnormal albumin levels could indicate kidney disease or malnutrition. Early detection helps guide treatment decisions.
Short name
Protein Electrophoresis (BCG)
Frequently asked questions
What does a high or low protein fraction mean?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy