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C-reactive protein (CRP) by nephelometry (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein made by your liver that rises in response to inflammation in your body.

Quick summary

["CRP helps track inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111567-4
Short code
S pyo DNA BAS NAA+n-prb-NCncRng
Synonyms
S pyo DNA BAS NAA+n-prb-NCncRng
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does CRP Measure?

CRP is a marker produced by your liver when your body is fighting inflammation. It can be elevated due to infections, injuries, or conditions causing chronic inflammation, such as arthritis or heart disease. Your doctor may use this test to check for signs of inflammation or to monitor treatment progress.

Your healthcare provider may order this test to assess inflammation levels, evaluate symptoms of conditions like infections, autoimmune diseases, or to monitor chronic illnesses such as heart disease or certain cancers.

CRP is often used alongside other tests to provide a fuller picture of your health. It’s particularly helpful in situations where symptoms aren’t clear-cut, such as in early-stage infections or inflammatory conditions.

A blood sample is taken from a vein, usually in your arm. The blood is processed to separate plasma, which is then analyzed using a nephelometry method to measure CRP levels.

You may feel a small pinch when the needle is inserted, but the procedure is quick and typically requires no special preparation. Avoid strenuous activity or eating heavy meals before the test to ensure accurate results.

Several factors can influence CRP levels, including recent infections, injuries, stress, smoking, or certain medications. Chronic conditions like obesity, diabetes, or heart disease can also affect CRP levels.

While CRP is a useful indicator of inflammation, it’s not definitive on its own. Your doctor will consider your overall health, symptoms, and other test results to interpret the results accurately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP levels often signal inflammation, which can be linked to infections, autoimmune diseases, or other inflammatory conditions. Lower-than-normal levels may indicate no active inflammation. However, CRP alone doesn’t diagnose a specific condition. It’s typically used as part of a broader evaluation to guide treatment decisions.

Short name

CRP (Plasma)

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests inflammation is present in your body. This could be due to infections, injuries, autoimmune diseases, or other health issues. Your doctor will review your symptoms and other test results to determine the cause and next steps.
Yes, lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. Reducing inflammation through a healthy diet, regular physical activity, and avoiding smoking may help lower CRP levels over time.
The frequency of CRP testing depends on your health condition and your doctor’s recommendations. Some people may need CRP tests regularly to monitor chronic conditions, while others may only need it occasionally for specific evaluations.
Avoid strenuous exercise or eating heavy meals 24 hours before your test. Stay hydrated and follow any specific instructions your healthcare provider gives you.
If your CRP test results are abnormal, your doctor will discuss them with you and may recommend further testing or changes to your treatment plan. They will consider your overall health and other factors to provide guidance tailored to your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy