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Serum or Plasma Probe for Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood, helping identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or kidney problems.

Quick summary

["Protein electrophoresis helps diagnose and monitor conditions affecting protein balance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97638-1
Short code
S pyo DNA Snv Ql NAA+n-prb
Synonyms
S pyo DNA Snv Ql NAA+n-prb
Category
coagulation
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Protein electrophoresis separates blood proteins into different fractions using an electric current. This process reveals the types and amounts of proteins, such as albumin, globulins, and others, which can be affected by various health conditions.

Why Might You Need This Test?

Your healthcare provider may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or to monitor conditions like kidney disease, liver disease, or certain cancers.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate proteins, which are analyzed for their distribution and concentration.

What Are Common Results?

Results are qualitative and described as patterns (e.g., 'normal distribution,' 'spiked globulin,' 'monoclonal spike'). These patterns help guide further testing or treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Protein electrophoresis is crucial for diagnosing conditions like multiple myeloma (a cancer of plasma cells), systemic amyloidosis, or other disorders affecting protein synthesis or breakdown. Abnormal patterns may indicate organ dysfunction or systemic diseases requiring targeted treatment.

Short name

Protein Electrophoresis Screening

Frequently asked questions

What does a 'qualitative' result mean?
A qualitative result provides a descriptive pattern rather than a numerical value. It helps identify if protein distribution is abnormal, which can signal underlying health issues that need further evaluation.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times and any follow-up tests required.
Can I eat or drink before this test?
No special preparation is needed for this test. However, follow any specific instructions your healthcare provider gives you, such as fasting for other related tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy