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Serum or plasma concentration of **progesterone** (total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone important for reproductive health, in your blood.

Quick summary

["Progesterone levels help track fertility, pregnancy, or hormone-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111012-1
Short code
S pyog.enz Ab Msmt Ser
Synonyms
S pyog.enz Ab Msmt Ser
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test to evaluate hormone balance, diagnose fertility issues, check for pregnancy, or monitor conditions like polycystic ovary syndrome (PCOS) or hormonal imbalances. It’s often done during the menstrual cycle or in response to symptoms like irregular periods or missed cycles.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Bring any medications or supplements you’re taking, as they could affect results. Avoid smoking or caffeine before the test if instructed.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick. The blood is then sent to a lab for analysis. Results are typically ready within 1–3 business days.

What the Results Mean

Results are compared to a reference range specific to your cycle phase (e.g., pre-ovulation, mid-cycle, or post-ovulation). Low levels may suggest ovulation issues, while high levels could indicate pregnancy or certain hormonal disorders. Always discuss results with your provider—they’ll interpret them in the context of your health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Progesterone

Frequently asked questions

What could affect my results?
Several factors can influence progesterone levels, including medications (e.g., birth control, steroids), stress, illness, or certain foods. Smoking, alcohol, and caffeine may also impact results. If you’re taking any of these, mention them to your provider before testing.
How often should I get this test?
The frequency depends on your health goals. For fertility tracking, tests may be done monthly or during specific cycle phases. If monitoring a condition like PCOS, your provider may recommend regular follow-ups. Never adjust testing without their guidance.
Can I take anything before or after the test?
Follow your provider’s instructions closely. Avoid smoking, excessive caffeine, or alcohol for 24 hours before testing. If you’re pregnant or breastfeeding, let your provider know—some tests may need adjustments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy