Serum or plasma substance concentration (mass concentration) for spygogen (sphingosine-1-phosphate)
This test measures the amount of sphingosine-1-phosphate, a signaling molecule involved in immune response and vascular health, in your blood.
["S1P helps regulate inflammation and blood vessel function; levels may be checked for conditions affecting these processes."]
Key facts at a glance
- LOINC
- 31658-8
- Short code
- S pyog.enz Ab Ser-aCnc
- Synonyms
- S pyog.enz Ab Ser-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal S1P levels, such as autoimmune diseases, vascular disorders, or certain cancers. It may also be part of routine monitoring for patients with known metabolic or inflammatory conditions.
What to Expect Before the Test
No special preparation is typically needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s instructions. Bring any medications you’re taking to your appointment.
Test Process
A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but the process is quick. You can usually resume normal activities immediately afterward.
What the Results Mean
Results are interpreted by your provider based on your clinical context. Elevated or low levels may indicate underlying health concerns, but they’re not standalone diagnoses. Follow-up testing or additional questions may be needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Sphingosine-1-phosphate (S1P) level
Frequently asked questions
What causes S1P levels to change?
Fasting may be recommended, but always confirm with your provider. Some tests are done on an empty stomach to avoid interference from food, while others may not require fasting. Your provider’s instructions are critical.
Can I take my medications before the blood draw?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy