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Urine Squamous Cell Area Ratio (or Urine Squamous Cell Density/Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence and relative amount of squamous cells in your urine, which may help assess urinary tract health or detect abnormalities like infections, inflammation, or certain cancers.

Quick summary

["This test can help identify urinary issues or early signs of disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45390-2
Short code
Squamous #/area UrnS LPF
Synonyms
Squamous #/area UrnS LPF
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-lpf
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urination, blood in urine, pain during urination, or if you’re at higher risk for urinary tract conditions. It can also be part of routine screening in certain cases, such as monitoring for bladder or kidney cancer.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected in the morning. Avoiding certain medications or foods (like cranberry juice) that might alter urine color for 24 hours before testing may be advised by your provider.

How the Test Works

A trained technician examines your urine sample under a microscope to count or compare the number of squamous cells (a type of skin cell found in urine) relative to other cells or substances. This helps determine if there’s an unusual presence or pattern.

What the Results Mean

Results are qualitative (descriptive) rather than numerical, focusing on whether the squamous cell count or pattern is within expected ranges or if it suggests abnormalities that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Squamous Cell Analysis

Frequently asked questions

High or unusual squamous cell counts in urine may indicate urinary tract infections, inflammation, or conditions like bladder cancer. However, squamous cells are normal in urine, so results alone shouldn’t diagnose a condition without additional testing.
This test is often used as part of a broader evaluation, such as a cystoscopy or biopsy, to guide further medical decisions.
What causes squamous cells to appear unusually in urine?
Squamous cells can appear in urine due to normal shedding from the urinary tract lining, but increased or abnormal patterns may signal infections, irritation, or structural changes. Certain medical conditions or treatments (like catheter use) can also influence results.
Can diet affect this test?
While diet itself rarely alters squamous cell counts, certain foods or medications may change urine appearance or composition. Always follow your provider’s specific instructions for pre-test preparation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy