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Serum or plasma concentration of porphyrin metabolites (specifically, coproporphyrin)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of coproporphyrin, a breakdown product of heme, in your blood. It helps identify conditions affecting heme synthesis or red blood cell breakdown.

Quick summary

["Coproporphyrin levels can signal potential blood disorders or metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50739-2
Short code
SRA porcine+LMW Pnl Ser
Synonyms
SRA porcine+LMW Pnl Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, abdominal pain, or unusual skin changes. It’s also used to monitor conditions like porphyria, anemia, or liver disease.

What to Expect During the Test

A simple blood draw is typically used. You’ll have a small needle inserted into your arm, and a small amount of blood will be collected into a tube. The process usually takes a few minutes.

Common Conditions Monitored

High levels of coproporphyrin can indicate inherited or acquired disorders that disrupt normal heme production, such as certain types of porphyria or hemolytic anemia. Your provider will interpret results in the context of your symptoms and medical history.

What the Results Mean

Results are compared to a baseline or reference range provided by your lab. Elevated levels may prompt further testing or evaluation of your blood, liver, or red blood cell function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated coproporphyrin levels often suggest an underlying metabolic disorder affecting heme synthesis or red blood cell breakdown. Low levels may be normal or could indicate other conditions that require further investigation by your healthcare team.

Short name

Coproporphyrin

Frequently asked questions

What triggers this test?
This test may be ordered if you have symptoms like fatigue, abdominal pain, or skin sensitivity to light, or if you have a family history of porphyria or other blood disorders.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can I eat or drink before this test?
You can eat and drink normally before the test unless your provider gives specific instructions. No fasting is required for this blood test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy