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Serum Creatinine (Creatinine, Kidney Function)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle metabolism that your kidneys filter out of your blood. It helps assess how well your kidneys are working.

Quick summary

["A creatinine test checks kidney function by measuring waste product levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110743-2
Short code
S rectivirgula IgG Msmt Ser
Synonyms
S rectivirgula IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does Creatinine Measure?

Creatinine is a byproduct of muscle breakdown and is naturally excreted by your kidneys. Elevated levels may indicate reduced kidney function, while lower levels could suggest overhydration or muscle loss. This test is often used alongside other markers to evaluate kidney health.

Why Is This Test Done?

Your healthcare provider may order a serum creatinine test to monitor kidney disease, diagnose conditions like chronic kidney disease, or assess how well medications are being processed by your kidneys. It’s also used in the evaluation of dehydration, muscle disorders, or fluid imbalances.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab for analysis. No special preparation is needed, but you may be asked to fast or avoid certain medications for a day or two before the test.

What Are Common Results?

Results are typically reported in milligrams per deciliter (mg/dL) or micromoles per liter (µmol/L). While reference ranges vary by lab, higher than expected levels may signal kidney problems, while lower levels could raise concerns about hydration or muscle mass.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health condition. For example, people with kidney disease may need tests every few months, while healthy individuals might only need it periodically or when symptoms arise.
What does a high creatinine level mean?
A high creatinine level often suggests your kidneys are not working as well as they should, possibly due to kidney disease, dehydration, or conditions like heart failure or diabetes. It’s important to discuss your results with your healthcare provider to understand the full picture.
Can diet affect my creatinine levels?
Yes, diet can influence creatinine levels. High-protein diets may temporarily increase creatinine because muscle breakdown produces more waste. Hydration status also matters—dehydration can raise levels, while overhydration may lower them. Always follow your doctor’s advice regarding dietary changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy