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Total Serum/Plasma Protein Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum or plasma. Proteins are essential for many bodily functions, including transporting nutrients, maintaining fluid balance, and supporting immune responses.

Quick summary

["Your blood protein levels help assess overall health and detect potential issues like dehydration, liver disease, or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49899-8
Short code
S rostrata IgE/IgE total %
Synonyms
S rostrata IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Done

Doctors may order this test to evaluate your health in several situations, such as checking for signs of kidney disease, liver problems, or malnutrition. It can also help diagnose conditions like edema (swelling), infections, or certain types of anemia. Sometimes, it’s used as part of a routine check-up or to monitor chronic conditions.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test if it’s part of a more complex evaluation, but this isn’t always the case. Bring any medications or supplements you’re taking to your appointment.

What Happens During the Test

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it’s usually over quickly. The blood sample is then sent to a lab for analysis.

What the Results Mean

Your results will show the total protein concentration in your blood. While specific reference ranges can vary by lab, lower levels might suggest conditions like kidney disease or malnutrition, while higher levels could indicate dehydration, liver disease, or certain inflammatory conditions. Your doctor will interpret the results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will contact you once they have the results, so keep their office number handy during your appointment.
Can I eat or drink anything before this test?
Most of the time, no special diet is required. However, if your doctor has instructed you to fast, follow their instructions carefully. If you’re unsure, ask your healthcare provider before the test.
Will I experience any side effects from the blood draw?
Most people experience only mild discomfort or bruising at the injection site. Rarely, there may be a slight swelling or redness. If you experience excessive pain, bleeding, or signs of infection (like increased redness or warmth), contact your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy