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Serum or Plasma Substance Concentration (Qualitative) for Renal Function Biomarker (e.g., cystatin C)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein-related substance in your blood that helps assess how well your kidneys are working. It may be used to monitor kidney function, especially in people with chronic conditions or those at risk for kidney problems.

Quick summary

["This test helps track kidney health and may be used alongside other tests to guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6138-2
Short code
S rostrata IgE Qn
Synonyms
S rostrata IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Kidneys filter waste and excess fluids from your blood. This test helps doctors check if your kidneys are working properly by measuring a specific protein that appears in the blood when kidney function declines. It can be useful for detecting early kidney damage or monitoring kidney disease progression.

When You Might Need This Test

Your doctor may order this test if you have symptoms like swelling, frequent urination, fatigue, or if you have a history of kidney disease, diabetes, high blood pressure, or other conditions that increase kidney risk. It may also be part of routine check-ups for people with chronic health conditions.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the test if it involves drawing blood. Drink plenty of water the day before if you’re having urine tests as part of kidney function studies. Avoid smoking or taking certain medications that could affect results.

What the Test Results Mean

Results are not given as a single number range since this is a qualitative test. Instead, your doctor will compare the presence or absence of this substance to your medical history and other test results to assess kidney function. High levels may indicate kidney problems, while normal levels suggest healthy filtering.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

None

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result (presence of this substance) may signal impaired kidney function. Your doctor will review your overall health, other test results, and symptoms to determine next steps, which could include further testing or adjustments to your treatment plan.
Can I eat or drink before this test?
Most likely, no special diet is required, but follow your doctor’s instructions. If this test is part of a broader kidney function panel, they may specify fasting or hydration needs. Always confirm with your healthcare provider.
How often will I need this test?
Frequency depends on your health condition. Some people with chronic kidney disease may need this test every few months, while others with stable health may only need it occasionally. Your doctor will set a schedule based on your individual needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy