Uropathogenic *Escherichia coli* (UPEC) DNA by Nucleic Acid Amplification Probe

Why This Test Is Used

Doctors may order this test if you have symptoms of a urinary tract infection (e.g., frequent urination, pain, or cloudy urine) and other tests (like a urine culture) are either negative or do not show the typical bacteria causing UTIs. It can also be used in cases of recurrent UTIs or infections that do not respond to standard antibiotics. This helps determine if the infection is caused by a strain resistant to common treatments or if other factors are involved.

How the Test Works

This test uses a special probe to detect genetic material (DNA) from *E. coli* bacteria in your urine. Unlike a traditional urine culture, which grows bacteria to identify them, this test directly measures the presence of specific genetic sequences linked to certain strains of *E. coli* that commonly cause UTIs. This can provide results more quickly.

What to Expect Before the Test

No special preparation is needed for this test. You will provide a urine sample, similar to a routine urine test. If you are taking antibiotics, let your healthcare provider know, as this may affect the results.

What the Results Mean

A positive result means the test detected genetic material from *E. coli* bacteria, suggesting that this strain may be causing your UTI. A negative result means no detectable genetic material was found, though other bacteria or causes of UTIs could still be present. Results should be interpreted by your healthcare provider in the context of your symptoms and medical history.