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Hypoxanthine, Xanthine, and Urate Panel, Urine

Published: August 9, 2026Updated: August 17, 2026

A urine test that measures hypoxanthine, xanthine, and urate, substances involved in purine metabolism and uric acid production.

Quick summary

["This panel helps evaluate how your body breaks down purines and produces uric acid."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
94397-7
Short code
SSC HypoXan Xan Urate Pnl Ur
Synonyms
SSC HypoXan Xan Urate Pnl Ur
Category
kidney
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This urine panel measures hypoxanthine, xanthine, and urate. These substances are related to purine metabolism, the process that produces uric acid, and can provide information about causes of uric acid buildup or kidney stones.

Why might I need this test?

Your clinician may order this test when there is concern about unusually high uric acid, recurrent kidney stones, or an inherited disorder of purine metabolism. It may also be used to follow the effects of medicines that alter uric acid production.

How is the test performed?

Urine is collected and sent to a laboratory, where the amounts of hypoxanthine, xanthine, and urate are measured. Your clinician may request a single urine sample or a timed collection, such as a 24-hour collection, depending on the purpose of the test.

How do I prepare for the test?

Follow your clinician or laboratory collection instructions exactly. For a timed collection, record the start and finish times and collect all urine during that period; the laboratory may also provide storage and delivery instructions.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urinary urate can occur with increased uric acid production, reduced kidney excretion, dehydration, or certain medicines. Changes in hypoxanthine and xanthine may indicate an inherited problem in purine breakdown, such as reduced xanthine oxidase activity. Results should be interpreted with symptoms, medical history, medications, and other kidney or stone tests.

Short name

Urinary purine panel

Frequently asked questions

Does this test measure the same thing as a serum uric acid test?
No. This panel measures uric acid-related substances in urine, while a serum uric acid test measures uric acid in blood. Your clinician may use both to understand how uric acid is being produced and excreted.
Do I need to fast before this test?
Fasting is generally not required unless your clinician specifically says otherwise. Diet, hydration, and some medicines can affect the results, so ask whether any medication or diet instructions apply.
Will this test diagnose gout or a kidney stone?
It may support evaluation of gout or stones, but it does not diagnose either condition by itself. Your clinician will interpret the panel with other examinations, laboratory results, and your medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy