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Serum Soluble Scleroderma-Related Anticardiolipin Antibody (IgG) Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures a type of antibody found in your blood that may be linked to conditions like lupus or other autoimmune diseases, including scleroderma.

Quick summary

["Helps assess risk for blood clots or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90239-5
Short code
ST2.soluble Ser IA-mCnc
Synonyms
ST2.soluble Ser IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects soluble anticardiolipin antibodies (IgG class) in your serum. These antibodies are proteins that can bind to phospholipids found in cell membranes, sometimes contributing to blood clotting or other immune-related complications.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of autoimmune diseases (e.g., fatigue, joint pain), a history of blood clots, or conditions like lupus or scleroderma. It can also be part of routine monitoring for patients at higher risk.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm in a clinic or lab setting. The process takes a few minutes.

What the Results Mean

Results are qualitative (present/absent) rather than numeric, indicating whether the antibody was detected. Elevated levels may suggest an autoimmune condition, but they’re not definitive on their own.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-Cardiolipin Antibody (IgG) Soluble Serum

Frequently asked questions

Why might I need this test?
Your doctor may order this test to investigate symptoms like unexplained blood clots, chronic fatigue, or autoimmune flare-ups. It’s also used in research or follow-up for patients with known connective tissue disorders.
What does a positive result mean?
A positive result means your blood contains detectable anticardiolipin antibodies. This can raise concern for autoimmune activity but isn’t diagnostic alone. Further testing or clinical correlation is needed.
Can lifestyle changes affect this test?
No, this test measures antibodies present in your blood at the time of testing. Lifestyle factors like diet or stress may influence overall health but don’t directly alter antibody levels detected here.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy