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Influenza Virus Antibody Screening (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that your immune system produces in response to previous exposure to the influenza virus. It helps determine if you may have been infected with flu virus at some point.

Quick summary

This test helps assess past flu exposure and may support vaccination decisions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86556-8
Short code
STAFFWHODECLINEDINFLUENZAVACCINE
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific antibodies (immunoglobulins) that your body creates to fight flu viruses. These antibodies are part of your immune response and can appear after infection or vaccination. The presence of these antibodies suggests prior exposure to the virus.

Why It’s Ordered

Doctors may order this test to evaluate whether someone has had flu exposure, especially if they are considering vaccination or need to confirm immunity. It can also be used in research or epidemiological studies to track flu spread.

How the Test Works

A blood sample is taken and analyzed to identify antibodies against influenza. The method typically involves an immunoassay (such as enzyme-linked immunosorbent assay or chemiluminescent immunoassay) to detect these antibodies in serum or plasma.

Sample Collection

A small amount of blood is drawn from a vein, usually in your arm. The blood sample is then processed and sent to a lab for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Influenza Antibody Test

Frequently asked questions

This test does not confirm a current flu infection but indicates whether you have developed immunity through prior exposure. It can help guide vaccination decisions, especially for individuals who may have had flu in the past but are unsure about their immunity status.
This test result alone does not determine whether you are currently infected with the flu. If you suspect you have the flu, consult your healthcare provider for appropriate care, such as rest, hydration, and possibly antiviral medications if needed.
What does a positive result mean?
A positive result means your blood contains antibodies against the influenza virus, suggesting you likely had flu at some point in the past. This does not guarantee immunity against future infections, as immunity can vary.
Can I get vaccinated even if I have a positive antibody test?
Yes, you can still get vaccinated. While a positive antibody test indicates prior exposure, vaccination remains the best way to protect yourself against future flu infections and provides broader protection against different flu strains.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy