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Serum or Plasma Total Protein by Bromocresol Purple (BCP) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which helps assess overall protein levels and kidney function.

Quick summary

["Total protein helps check for conditions like malnutrition, kidney disease, or liver problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76054-6
Short code
ST Amp L-II
Synonyms
ST Amp L-II
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate protein balance in your body. High or low protein levels can signal underlying health issues, such as kidney disease, liver disorders, or malnutrition. It’s also used to monitor conditions like edema (fluid retention) or protein-losing syndromes.

What Does the Result Mean?

Results are compared to a general reference range for healthy adults. Very high or very low levels may require further medical evaluation to determine the cause.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The blood is separated into serum (liquid part after clotting) or plasma (liquid part before clotting) for testing.

What Are Common Causes of Abnormal Results?

High protein levels may occur with dehydration, multiple myeloma, or severe infections. Low protein levels can result from kidney disease, liver failure, or conditions that cause excessive protein loss (e.g., protein-losing enteropathy).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein testing is critical for diagnosing and managing conditions affecting protein synthesis, absorption, or retention. It helps identify systemic issues like malnutrition, chronic kidney disease, or inflammatory states that may not show other symptoms.

Short name

Total Protein

Frequently asked questions

What does a high total protein level usually indicate?
A high total protein level may suggest conditions like severe dehydration, multiple myeloma, or chronic infections. It can also occur in certain types of kidney disease or after significant blood loss.
What does a low total protein level usually indicate?
A low total protein level often points to kidney disease, liver failure, malnutrition, or conditions causing excessive protein loss (e.g., severe diarrhea or vomiting). Your doctor may also check for protein-losing syndromes or immune disorders.
Can diet affect my total protein test results?
Yes, diet can influence protein levels. High-protein diets may temporarily raise results, while low-protein diets could lower them. Your doctor may recommend fasting or specific dietary adjustments if needed for accurate interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy