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Serum or Plasma Total Protein by Bromocresol Purple Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, including albumin and other proteins like globulins.

Quick summary

["Total protein helps assess overall protein balance and potential liver or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76050-4
Short code
ST Amp L-V4
Synonyms
ST Amp L-V4
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, or malnutrition. It can also help diagnose or monitor conditions like nephrotic syndrome or severe dehydration.

What Does the Result Mean?

Higher-than-normal results might suggest liver disease, overhydration, or certain types of cancer. Lower-than-normal results could indicate malnutrition, kidney disease, or severe burns. Your results will be interpreted by your doctor in the context of your overall health.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing.

What Are Common Causes of Abnormal Results?

Abnormal protein levels can result from conditions like cirrhosis (liver disease), chronic kidney disease, severe infections, or certain medications. Lifestyle factors, such as poor nutrition, can also influence protein levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

Why might my total protein test result be higher than expected?
Higher-than-normal protein levels may be due to conditions like liver disease, overhydration, or certain cancers. Your doctor will review your medical history and other test results to determine the cause.
What if my total protein test is lower than expected?
Lower-than-normal protein levels might indicate malnutrition, kidney disease, severe burns, or chronic infections. Your doctor will discuss your symptoms and other test results to understand what’s happening.
Does diet affect my total protein test results?
Yes, diet can influence protein levels. Eating a balanced diet with adequate protein intake helps maintain normal levels. If you suspect dietary issues, talk to your doctor or dietitian for guidance.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy