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Staphylococcus Culture (with Antimicrobial Susceptibility Testing)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of *Staphylococcus* bacteria in a blood sample and determines how well antibiotics work against them.

Quick summary

["Identifies bacterial infection and antibiotic resistance in blood samples."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20967-6
Short code
Staphylococcus Mlk Cult
Synonyms
Staphylococcus Mlk Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a Staphylococcus culture if you have symptoms like fever, chills, or unexplained infections that could be caused by bacteria. It helps confirm whether bacteria are present and guides treatment choices.

How the Test Works

A small blood sample is taken and grown in a lab to detect *Staphylococcus* bacteria. If bacteria are found, additional tests determine how they respond to different antibiotics.

What to Expect Before the Test

No special preparation is needed. You may experience mild discomfort from the needle, but it’s usually brief. Avoid taking antibiotics before the test if your doctor instructs you to, as they may affect results.

Possible Results and Their Meaning

A positive result means *Staphylococcus* bacteria were found. The antibiotic susceptibility report will show which drugs are most effective against the identified strain. A negative result means no bacteria were detected in this sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing bloodstream infections caused by *Staphylococcus*, guiding appropriate antibiotic therapy to prevent complications like sepsis. Resistance patterns help tailor treatment to avoid ineffective or harmful medications.

Short name

Staph Culture

Frequently asked questions

What does a positive culture mean?
A positive culture confirms the presence of *Staphylococcus* bacteria in your blood. This means you likely have an infection, and your doctor will use the antibiotic susceptibility report to choose the best treatment.
How long does it take to get results?
Results typically take 3–7 days, depending on lab processing. Some labs may provide preliminary findings sooner, but final susceptibility testing can take longer.
Can I take antibiotics before the test?
No, avoid antibiotics unless directed by your doctor. Taking them before testing may skew results and delay accurate diagnosis.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy