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Serum or plasma concentration of total protein (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which helps assess overall protein status and detect potential issues like malnutrition, kidney disease, or liver problems.

Quick summary

["A protein screening test can reveal important health clues about your blood composition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10093-3
Short code
ST I-Amp 6ms L-V6
Synonyms
ST I-Amp 6ms L-V6
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Protein is essential for many bodily functions, including transporting nutrients, supporting immune function, and maintaining tissue integrity. Low or high protein levels can signal underlying health concerns that may require further evaluation.

What to Expect During the Test

This test is typically done by drawing blood from a vein in your arm. The sample is sent to a lab where it is analyzed to determine protein concentration. Results are usually available within a few days.

Common Conditions Affecting Protein Levels

High protein levels might be seen in conditions like dehydration, multiple myeloma, or certain infections. Low protein levels can occur with kidney disease, liver problems, or chronic malnutrition.

How Protein Levels Are Interpreted

While exact reference ranges vary by lab, qualitative screening provides a general direction. Clinicians may order additional tests if protein levels are abnormal to pinpoint the cause.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein level screening

Frequently asked questions

What causes protein levels to be abnormal?
Abnormal protein levels can result from conditions affecting protein synthesis (e.g., liver disease), protein loss (e.g., kidney disease), or fluid imbalances (e.g., dehydration). Your healthcare provider may also consider medications, diet, or recent illness when reviewing results.
How often should I get this test?
The frequency depends on your health status. Routine screening for healthy adults is usually not recommended unless advised by your doctor. If you have a chronic condition like kidney or liver disease, your provider may schedule regular monitoring.
Can diet affect protein test results?
Yes, diet can influence protein levels. High-protein diets may temporarily raise protein concentrations, while severe protein deficiencies (e.g., from poor nutrition) can lower them. Always follow your healthcare provider’s guidance on timing and diet before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy