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Serum or Plasma Protein Electrophoresis with Bromocresol Green (BCG) Dye Binding Assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood, often used to evaluate conditions affecting protein levels or patterns, such as liver disease, kidney problems, or certain cancers.

Quick summary

["This test helps identify abnormal protein patterns that may signal underlying health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63426-1
Short code
ST Spec Ql NAA+probe
Synonyms
ST Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test separates blood proteins into categories (e.g., albumin, globulins) using electrophoresis, a technique that moves proteins through a gel based on size and charge. Bromocresol green dye binds to proteins, allowing for visual or quantitative assessment of each fraction. This helps detect shifts in protein composition that may indicate conditions like inflammation, infections, or metabolic disorders.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or signs of liver/kidney disease. It’s also used for diagnosing conditions like multiple myeloma, amyloidosis, or certain autoimmune diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is processed to separate serum or plasma, which is then analyzed. No special preparation is needed, but fasting may be advised if your test includes additional metabolic protein assessments.

What to Expect During the Test

The procedure takes about 15 minutes. You may feel slight discomfort at the needle site, but most people tolerate it well. Results are usually ready within 24–48 hours, depending on lab workflows.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Electrophoresis

Frequently asked questions

Why might my results be important?
Abnormal protein patterns can reveal conditions like liver disease (e.g., cirrhosis), kidney disease, or protein-losing syndromes. For example, low albumin may signal malnutrition or liver dysfunction, while elevated alpha-2 globulins could indicate inflammation or chronic disease. This test is also critical for monitoring treatment responses in cancers or autoimmune disorders.
How long will I need to wait for results?
Results are typically available within 24–72 hours, but timing varies by lab. Your healthcare provider will discuss findings with you during your follow-up visit.
Can I eat or drink before this test?
No special diet is required unless your provider specifies otherwise. However, if your test includes additional components (e.g., metabolic proteins), fasting may be necessary—ask your lab or provider for specifics.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy