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Serum or Plasma Substance Concentration (Mass Concentration) for Immunoglobulin G (IgG) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.

Quick summary

["IgG levels can indicate immune function, infection, or certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8620-7
Short code
ST-T seg Imp EKG
Synonyms
ST-T seg Imp EKG
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is the most common type of antibody in your blood. It plays a key role in defending against bacteria and viruses. This test helps doctors assess your immune system’s ability to fight infections and provides information about conditions like immune deficiencies, chronic infections, or autoimmune diseases.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of a weakened immune system, such as frequent infections, unexplained fatigue, or if you’re being treated for conditions like lupus, rheumatoid arthritis, or HIV. It may also be used to monitor immune responses during treatments like chemotherapy or for newborns to check for maternal antibodies.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re having a 24-hour urine test (if applicable), you’ll need to collect urine samples over a full day. Always follow your provider’s instructions.

What to Expect During the Test

The blood draw is quick and typically painless. If you’re uncomfortable, let your healthcare provider know. If this is a urine test, you’ll need to follow specific collection guidelines to ensure accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Level

Frequently asked questions

How Does IgG Relate to My Health?
IgG levels can help identify if your immune system isn’t working as it should, which is important for conditions like HIV, cancer treatments, or congenital immune disorders. Your doctor will discuss any abnormal results with you.
What Are Normal IgG Levels?
Normal IgG levels vary by age and health status. Your doctor will interpret your results in the context of your overall health and medical history, not just a single number.
Can IgG Levels Change Over Time?
Yes, IgG levels can change due to infections, medications, immune responses, or underlying health conditions. Regular monitoring may be needed if you have a chronic illness or are undergoing treatment that affects your immune system.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy