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Serum or Plasma Aldosterone Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands. It helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much salt and water your body retains, which affects your blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10116-2
Short code
ST wave ED L-V5
Synonyms
ST wave ED L-V5
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to check for conditions affecting your blood pressure, such as primary aldosteroneism (a rare disorder where your adrenal glands produce too much aldosterone). It can also help diagnose or monitor conditions like hypertension (high blood pressure), adrenal tumors, or kidney problems that may influence hormone levels.

What to Expect Before the Test

No special preparation is needed for this test. If it’s a blood draw, you may have a small needle inserted into your arm, and you’ll feel a brief pinch. If it’s a urine sample, you’ll collect a sample over 24 hours, but no special diet or activity restrictions apply.

What the Results Mean

Results help doctors determine if your hormone levels are too high or too low. High levels might suggest conditions like aldosteronism, while low levels could indicate adrenal insufficiency or other hormonal imbalances. Your doctor will discuss these results in the context of your overall health.

Common Conditions Monitored

This test is often used to diagnose or manage conditions like hypertension, adrenal adenomas, or congenital adrenal hyperplasia. It may also be part of evaluating patients with symptoms like unexplained high blood pressure, frequent urination, or fatigue.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Aldosterone

Frequently asked questions

What causes abnormal aldosterone levels?
Abnormal aldosterone levels can be caused by conditions like primary aldosteronism (where your adrenal glands overproduce aldosterone), kidney diseases, certain medications (e.g., potassium-sparing diuretics), or adrenal tumors. Low levels may result from adrenal insufficiency, kidney failure, or medications that suppress hormone production.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition and symptoms. Some patients may need it yearly, while others may require more frequent monitoring if they have chronic conditions like hypertension or adrenal disorders.
Can diet or exercise affect this test?
Dietary changes like high salt intake or certain medications may influence aldosterone levels, so your doctor may provide specific instructions. Generally, avoiding extreme dietary changes before testing is recommended, but always follow your healthcare provider’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy