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Serum or plasma concentration of vitamin D binding protein (DBP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein in your blood. It helps assess how well vitamin D is transported in your body.

Quick summary

["Understanding your vitamin D binding protein levels can help evaluate vitamin D metabolism and potential deficiencies or excesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10121-2
Short code
ST wave MD L-I
Synonyms
ST wave MD L-I
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms related to vitamin D metabolism, such as bone pain, muscle weakness, or unexplained fatigue. It may also be part of a broader evaluation for conditions like hypoparathyroidism, kidney disease, or certain genetic disorders affecting protein function.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood draw, where a small amount of blood is taken from a vein in your arm. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

Results show the concentration of vitamin D binding protein in your blood. While reference ranges vary by lab, abnormal levels may indicate issues with vitamin D transport or related metabolic processes.

Common Conditions Linked to DBP Levels

Changes in DBP levels can be associated with conditions like vitamin D deficiency, kidney disease, or certain genetic disorders. High levels might also occur in conditions affecting protein synthesis or liver function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D Binding Protein (DBP) Level

Frequently asked questions

Why might my doctor want to check my vitamin D binding protein levels?
Your doctor may check this level if they suspect a vitamin D-related issue, such as improper vitamin D absorption, kidney problems, or genetic disorders that affect protein function. It can also help monitor conditions like hypoparathyroidism or hypercalcemia.
What does a low or high DBP level mean?
Low levels might suggest problems with vitamin D transport or metabolism, while high levels could indicate conditions affecting protein production or kidney function. Always discuss results with your healthcare provider for personalized interpretation.
Do I need to avoid certain foods or supplements before this test?
No specific dietary restrictions apply, but inform your provider about any medications, especially blood thinners, to ensure safe testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy