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Serum or Plasma Aldosterone Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance in your body.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which affects your blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10123-8
Short code
ST wave MD L-III
Synonyms
ST wave MD L-III
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to check for conditions that affect your blood pressure, such as primary aldosteroneism (a rare disorder where your adrenal glands produce too much aldosterone), or to evaluate symptoms like high blood pressure, low potassium levels, or signs of adrenal gland issues. It may also be used in diagnosing conditions like hyperaldosteronism or to monitor treatment for related disorders.

What to Expect Before the Test

No special preparation is usually needed, but your doctor might ask you to avoid certain medications or dietary restrictions for a few days before testing. If you’re taking potassium-sparing diuretics (like spironolactone), you may need to stop them temporarily or adjust your dose as directed by your healthcare provider.

What the Test Involves

A blood sample will be taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the procedure is quick and usually doesn’t cause discomfort afterward. The sample is then sent to a lab for analysis.

What the Results Mean

Results are compared to standard reference ranges, but they can vary slightly depending on the lab. High aldosterone levels may indicate conditions like hyperaldosteronism, while low levels could suggest adrenal insufficiency or other hormonal imbalances. Your doctor will discuss the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Aldosterone level

Frequently asked questions

What causes high aldosterone levels?
High aldosterone levels are often caused by primary hyperaldosteronism (a tumor or overactivity of one or both adrenal glands), certain medications (like steroids or some blood pressure drugs), or conditions like chronic kidney disease. It can lead to high blood pressure, low potassium levels, and other health risks if untreated.
What causes low aldosterone levels?
Low aldosterone levels may result from adrenal gland disorders (such as Addison’s disease), certain medications (like potassium-wasting diuretics), or severe illness that affects hormone production. Symptoms may include fatigue, low blood pressure, or salt cravings.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, symptoms, and treatment plan. Regular monitoring may be needed if you have a known hormonal disorder or are taking medications that affect aldosterone levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy