Succinyladenosine/Creatinine Ratio, Urine
This urine test measures succinyladenosine relative to creatinine. The ratio can help evaluate purine metabolism, particularly when adenosine deaminase deficiency is suspected.
["An elevated urine succinyladenosine/creatinine ratio may indicate abnormal purine metabolism or adenosine deaminase deficiency."]
Key facts at a glance
- LOINC
- 59214-7
- Short code
- Succinyladenosine/Creat Ur-sRto
- Synonyms
- Succinyladenosine/Creat Ur-sRto
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures succinyladenosine, a metabolite produced during purine metabolism, in urine. The result is divided by the urine creatinine concentration to help account for differences in urine concentration.
Why might I need this test?
The test may be used to help evaluate suspected adenosine deaminase deficiency, an inherited condition that affects the breakdown of adenosine. It may also be ordered when symptoms or other findings suggest a disorder of purine metabolism.
How is the test performed?
A urine sample is collected and analyzed in a laboratory. The laboratory reports the urine succinyladenosine concentration relative to the creatinine concentration in the same sample.
How do I prepare for the test?
Follow the collection instructions provided by your clinician or laboratory. This may be a first-morning or spot urine sample, and fasting is usually not required unless your clinician specifically requests it.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An elevated succinyladenosine/creatinine ratio may indicate increased breakdown of adenosine and can occur with adenosine deaminase deficiency. Results should be interpreted with symptoms, medical history, and other laboratory tests because urine levels can also be affected by urine concentration and temporary changes in metabolism. A low or normal result does not by itself exclude every inherited metabolic disorder.
Short name
Urine succinyladenosine/creatinine ratio
Frequently asked questions
Why is creatinine included in the result?
Does this test require fasting?
Does an elevated result confirm a genetic disorder?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy