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Succinylcholine plasma concentration (qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence or level of succinylcholine, a medication used during certain types of surgery to help relax muscles.

Quick summary

["Succinylcholine is a short-acting muscle relaxant; this test helps monitor its effect in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11201-1
Short code
Succinylcholine IgE Qn
Synonyms
Succinylcholine IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to find out whether your body may react badly to succinylcholine, a medication that relaxes your muscles during anesthesia and certain medical procedures. Some people have a sensitivity or allergic-type reaction to this drug, and knowing about it ahead of time helps your care team choose safer treatment options for you.

Doctors may order this test if you’re scheduled for surgery that requires muscle relaxation, such as general anesthesia. It helps ensure the medication is working properly and at the right dose to prevent excessive muscle weakness or complications like respiratory issues.

Before the test, tell your healthcare provider about all prescription drugs, over-the-counter medicines, supplements, and herbal products you take, because some of them can affect the results. You will likely be asked about your health history and any past reactions to anesthesia. In most cases, a small blood sample is drawn from a vein in your arm.

No special preparation is needed. You’ll likely have a blood sample drawn from a vein in your arm, similar to other blood tests. If you’re already receiving succinylcholine, your provider may adjust timing based on your medical needs.

Your results show whether you have a typical response to succinylcholine or whether you may be at risk for a serious reaction. If the test suggests sensitivity or an allergic-type response, your care team will usually avoid this medication and use alternative anesthetic agents instead. Your provider will explain what your specific results mean for any future procedures.

Since this is a qualitative test, results are typically reported as either 'present' or 'not detected.' If succinylcholine is detected, it confirms the medication is active in your system. If absent, it may indicate the drug has broken down or was administered too early.

This test is considered very safe. If a blood sample is taken, you may feel a quick sting or pinch at the needle site, and mild bruising or soreness afterward is possible, but serious complications are rare. Keep in mind that no test is perfect, so always tell your provider about any past reaction to anesthesia, even if your results come back normal.

Blood tests carry a small risk of bruising, discomfort, or infection at the needle site. If you have a bleeding disorder or take blood thinners, discuss this with your provider before testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

Succinylcholine is used to facilitate intubation (breathing tube placement) or to prevent excessive muscle movement during surgery. Abnormal levels could suggest improper dosing, allergic reactions, or metabolic issues (e.g., pseudocholinesterase deficiency), which may require medical intervention.
Will this test confirm whether I am truly allergic to succinylcholine or only sensitive to it?
No, this test only measures the medication’s presence in your blood. Allergic reactions would be assessed clinically by your healthcare provider, including symptoms like rash, difficulty breathing, or muscle pain.
In most cases, you can eat and drink normally before this test, but always follow the specific instructions your healthcare team gives you. If other testing is planned the same day that requires fasting, such as certain blood work, your provider will let you know what to avoid and for how long.
You can eat and drink normally unless instructed otherwise by your provider. No fasting is required for this test.
Results are typically available within 1–2 business days, depending on lab processing times. Your healthcare provider will discuss them with you during your follow-up.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy