Succinylcholine plasma concentration (qualitative)
This test measures the presence or level of succinylcholine, a medication used during certain types of surgery to help relax muscles.
["Succinylcholine is a short-acting muscle relaxant; this test helps monitor its effect in your bloodstream."]
Key facts at a glance
- LOINC
- 11201-1
- Short code
- Succinylcholine IgE Qn
- Synonyms
- Succinylcholine IgE Qn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test is done to find out whether your body may react badly to succinylcholine, a medication that relaxes your muscles during anesthesia and certain medical procedures. Some people have a sensitivity or allergic-type reaction to this drug, and knowing about it ahead of time helps your care team choose safer treatment options for you.
Doctors may order this test if you’re scheduled for surgery that requires muscle relaxation, such as general anesthesia. It helps ensure the medication is working properly and at the right dose to prevent excessive muscle weakness or complications like respiratory issues.
Before the test, tell your healthcare provider about all prescription drugs, over-the-counter medicines, supplements, and herbal products you take, because some of them can affect the results. You will likely be asked about your health history and any past reactions to anesthesia. In most cases, a small blood sample is drawn from a vein in your arm.
No special preparation is needed. You’ll likely have a blood sample drawn from a vein in your arm, similar to other blood tests. If you’re already receiving succinylcholine, your provider may adjust timing based on your medical needs.
Your results show whether you have a typical response to succinylcholine or whether you may be at risk for a serious reaction. If the test suggests sensitivity or an allergic-type response, your care team will usually avoid this medication and use alternative anesthetic agents instead. Your provider will explain what your specific results mean for any future procedures.
Since this is a qualitative test, results are typically reported as either 'present' or 'not detected.' If succinylcholine is detected, it confirms the medication is active in your system. If absent, it may indicate the drug has broken down or was administered too early.
This test is considered very safe. If a blood sample is taken, you may feel a quick sting or pinch at the needle site, and mild bruising or soreness afterward is possible, but serious complications are rare. Keep in mind that no test is perfect, so always tell your provider about any past reaction to anesthesia, even if your results come back normal.
Blood tests carry a small risk of bruising, discomfort, or infection at the needle site. If you have a bleeding disorder or take blood thinners, discuss this with your provider before testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
Succinylcholine is used to facilitate intubation (breathing tube placement) or to prevent excessive muscle movement during surgery. Abnormal levels could suggest improper dosing, allergic reactions, or metabolic issues (e.g., pseudocholinesterase deficiency), which may require medical intervention.
No, this test only measures the medication’s presence in your blood. Allergic reactions would be assessed clinically by your healthcare provider, including symptoms like rash, difficulty breathing, or muscle pain.
You can eat and drink normally unless instructed otherwise by your provider. No fasting is required for this test.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy