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Succinylcholine Metabolite (Plasma/Serum) – Quantitative

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of succinylcholine’s active metabolite in your blood, which helps assess how your body processes this medication used during anesthesia.

Quick summary

["This test helps monitor drug metabolism and safety during anesthesia procedures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102614-5
Short code
Succinylcholine IgE RAST
Synonyms
Succinylcholine IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Succinylcholine is a fast-acting muscle relaxant used during surgery or intubation. After administration, it breaks down into its active metabolite, which remains in your bloodstream. This test quantifies the concentration of that metabolite to evaluate how quickly your body clears the drug, ensuring proper dosing and minimizing side effects like prolonged muscle paralysis.

Why Might You Need This Test?

Your healthcare provider may order this test if you’re receiving succinylcholine during anesthesia, particularly if you have conditions that might slow drug metabolism (e.g., liver disease, certain genetic factors). It helps ensure safe and effective use of the medication.

How Is the Sample Collected?

A blood sample will be drawn from a vein in your arm. The blood is processed to separate plasma or serum for testing. This is typically done shortly after you receive succinylcholine during anesthesia.

What Are Possible Results?

Results are reported as a concentration value (e.g., micrograms per milliliter) of the metabolite. Higher-than-expected levels may indicate slower drug clearance, while lower levels suggest faster metabolism. Your provider will interpret results in the context of your clinical situation.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need this test if I’m just having surgery?
Even routine surgeries may require precise dosing of muscle relaxants like succinylcholine. This test helps ensure the drug wears off safely after the procedure, preventing complications such as breathing difficulties or prolonged paralysis.
What if my results are outside the expected range?
Your healthcare provider will review the results with you and may adjust your anesthesia plan if needed. For example, if levels are high, they might slow the administration of other medications or monitor you more closely during recovery.
Can I eat or drink before this test?
You may eat and drink normally unless instructed otherwise by your provider. Since this test is performed during anesthesia, fasting requirements depend on the timing of your surgery and may be specified by your anesthesiologist.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy