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Sufentanil/Creatinine Ratio — Confirmatory Method

Published: August 9, 2026Updated: August 16, 2026

This confirmatory test measures the amount of sufentanil relative to creatinine in the submitted specimen.

Quick summary

["The test can identify and quantify sufentanil exposure, which may explain sedation or breathing problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86610-3
Short code
SUFentanil/Creat Ur Cfm
Synonyms
SUFentanil/Creat Ur Cfm
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Sufentanil is a strong opioid pain medicine. This test measures its amount in a specimen and compares it with the specimen's creatinine level, which can help account for how concentrated or dilute the sample is.

Why might I need this test?

This test may be used to confirm suspected opioid exposure or monitor whether sufentanil is present in a specimen. It may be considered when a person has unexplained sedation, slowed breathing, or another possible effect of an opioid.

How is the test performed?

The laboratory uses a validated confirmatory method to identify and measure sufentanil. Creatinine is measured as well, and the results are reported as a ratio when appropriate.

How do I prepare for the test?

Follow the specimen collection instructions provided by the laboratory or healthcare professional. Tell the clinician about all medicines or drugs you have used, but do not stop prescribed medication without medical advice.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Sufentanil/creatinine ratio

Frequently asked questions

What does a positive result mean?
It means sufentanil was detected in the specimen. The result may support recent exposure but does not by itself determine the dose taken or whether someone is experiencing toxicity.
Why is the result reported with creatinine?
Creatinine is used as a reference for specimen concentration. Comparing sufentanil with creatinine can reduce the effect of differences in how concentrated or dilute the specimen is.
Can this test show when sufentanil was taken?
Not precisely. The result can suggest recent exposure, but interpretation depends on the specimen type, collection time, dose, route of use, and the laboratory's testing method.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy