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Sulfatide (Serum) Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sulfatide, a type of glycolipid found in your blood serum. Sulfatides are involved in cell signaling and nerve function, and their levels can be evaluated for certain inherited conditions.

Quick summary

Sulfatides may be checked if you have symptoms or a family history linked to rare genetic disorders affecting lipid metabolism.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111295-2
Short code
Sulfatide IgG Msmt Ser
Synonyms
Sulfatide IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms such as developmental delays, neurological issues, or other signs of metabolic disorders. It’s also used in genetic testing for conditions like Sanfilippo syndrome or other lysosomal storage diseases where sulfatide buildup is known to occur.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample during a routine clinic visit or lab procedure. If you’re fasting, follow your provider’s instructions.

How the Test Works

Blood is drawn from a vein in your arm. The sample is then analyzed to measure sulfatide concentration using a specialized laboratory method, often involving high-performance liquid chromatography (HPLC) or similar techniques.

What the Results Mean

Results are compared to reference ranges specific to the lab. Elevated levels may indicate inherited metabolic disorders, while very low levels might suggest other conditions affecting lipid metabolism or nerve function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal sulfatide levels can signal genetic disorders that disrupt normal cell function, particularly in the nervous system. Early detection is important for managing symptoms and planning treatment options, such as enzyme replacement therapy for certain lysosomal storage diseases.

Short name

Sulfatide Level

Frequently asked questions

What causes sulfatide levels to be checked?
Sulfatide levels are checked primarily when there is a suspicion of inherited metabolic disorders, such as Sanfilippo syndrome or other lysosomal storage diseases. Your doctor may also order this test if you have a family history of these conditions or if symptoms like developmental delays or neurological problems are present.
How is the test performed?
The test involves drawing blood from a vein in your arm. The blood sample is then sent to a laboratory where it is analyzed using advanced techniques, such as high-performance liquid chromatography (HPLC), to measure sulfatide concentration.
What do my results mean?
Your results will be compared to standard reference ranges. Elevated levels may suggest inherited metabolic disorders, while very low levels could indicate other conditions affecting lipid metabolism. Always discuss your results with your healthcare provider for personalized interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy