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Sulfatide in Serum (or Plasma) by High-Performance Liquid Chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sulfatide, a type of glycolipid found in your blood, which plays a role in cell signaling and nerve function. It may be checked to evaluate conditions affecting lipid metabolism or neurological health.

Quick summary

["Sulfatide levels can help diagnose or monitor rare genetic disorders or metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31671-1
Short code
Sulfatide IgM Ser-aCnc
Synonyms
Sulfatide IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a family history suggestive of metabolic disorders, such as Gaucher disease, Niemann-Pick disease, or other lipid storage disorders. It may also be part of a broader evaluation for neurological symptoms like developmental delays, movement disorders, or cognitive impairment.

What to Expect Before the Test

No special preparation is typically required. You may have a blood sample drawn from a vein in your arm, or in some cases, a urine sample may be collected. Always follow your healthcare provider’s instructions for fasting or other preparations if specified.

What the Test Results Mean

Results are interpreted by your healthcare provider based on your clinical picture, symptoms, and other test findings. Elevated levels may indicate certain metabolic disorders, while very low levels could suggest inherited conditions affecting lipid processing.

Common Conditions Monitored

This test is often used in the context of diagnosing or managing rare genetic disorders linked to abnormal lipid metabolism, such as lysosomal storage diseases. It may also be part of research or specialized clinical studies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Sulfatide Level

Frequently asked questions

What does a high sulfatide level indicate?
A high sulfatide level may suggest an underlying metabolic disorder, such as Niemann-Pick disease type B or other lysosomal storage conditions. Your provider will discuss this with you in the context of your symptoms and medical history.
What does a low sulfatide level indicate?
Low sulfatide levels are less commonly evaluated in isolation but may be part of broader testing for genetic or metabolic disorders affecting lipid metabolism. Further evaluation would depend on your clinical presentation.
How often should I get this test?
The frequency of this test depends entirely on your healthcare provider’s recommendations. If you have a known condition affecting sulfatide metabolism, they may schedule regular follow-ups. Otherwise, it is usually ordered as needed for specific evaluations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy