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Total Serum IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions.

Quick summary

["IgE levels help identify allergies or immune responses to certain triggers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61272-1
Short code
Sunflower Seed IgE/IgE total %
Synonyms
Sunflower Seed IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgE Measure?

IgE, or Immunoglobulin E, is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. High levels of IgE can indicate allergies, asthma, or other allergic conditions. This test helps doctors determine if you have an allergic reaction or an immune response that needs further evaluation.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, rash, or breathing difficulties that suggest allergies. It can also be used to monitor conditions like asthma or chronic urticaria (hives). Sometimes, it’s part of a broader evaluation for immune-related disorders.

What to Expect Before the Test

You won’t need any special preparation for this blood test. A healthcare provider will draw blood from a vein in your arm. The process is quick and usually painless, though you might feel a slight pinch. If you’re on blood thinners or have a history of bleeding issues, let your doctor know before the test.

What to Expect During the Test

The blood sample will be sent to a lab for analysis. The test typically takes a few days to return results, depending on lab processing times. Your doctor will discuss the results with you once they’re ready, focusing on whether your IgE levels are within normal ranges or if further testing is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

How Often Should I Get This Test?
The frequency depends on your symptoms and medical needs. If you have allergies or asthma, your doctor may recommend regular monitoring. If you’re undergoing allergy immunotherapy (like allergy shots), tests might be done periodically to track changes in your IgE levels.
What Are Normal IgE Levels?
There’s no single ‘normal’ range for everyone, as it varies by age, health, and other factors. Your doctor will compare your results to a reference range specific to your lab and your individual health profile. High or low levels can signal different conditions, so results are interpreted in the context of your overall health.
Can Diet or Supplements Affect IgE Levels?
Dietary changes alone won’t directly alter IgE levels, but certain foods or supplements (like omega-3 fatty acids or probiotics) may influence immune function indirectly. If you suspect your diet could be affecting your symptoms, discuss it with your doctor before making changes, especially if you’re undergoing allergy testing or treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy