Syphilis serology (screening and confirmatory) during pregnancy
This test checks for syphilis antibodies in your blood to monitor your health and the safety of your baby during pregnancy.
Early detection helps manage syphilis and prevent complications for both you and your baby.
Key facts at a glance
- LOINC
- 75181-8
- Short code
- SURVEILLANCESTAGEOFSYPHILISDURINGPREGNANCY
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cdc-cs
- CPT
- 86592
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have risk factors for syphilis, such as multiple sexual partners, a history of sexually transmitted infections (STIs), or exposure to someone with syphilis. It is also part of routine prenatal care to ensure timely treatment if syphilis is present.
How the Test Works
The test uses blood drawn from a vein to detect antibodies against syphilis bacteria. Two types of tests are often performed: a screening test (qualitative) and a confirmatory test (if the screening is positive). These tests help identify whether syphilis is active or past infection.
What to Expect During the Test
You will lie down while a healthcare provider inserts a needle into your arm to collect a small amount of blood. The process takes a few minutes, and you may feel a brief pinch. The blood is then sent to a lab for testing.
What the Results Mean
Results may be positive, negative, or inconclusive. A positive result means syphilis antibodies are present, which could indicate past or current infection. Follow-up testing or treatment may be recommended based on the results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Syphilis test (pregnancy)
Frequently asked questions
What does a positive test result mean?
How often should I get this test during pregnancy?
Can I take anything special before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy