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Serum Creatinine (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10081-8
Short code
S' wave dur L-V6
Synonyms
S' wave dur L-V6
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a family history of kidney disease. It can also be used to check for kidney problems before surgery or during treatment for certain illnesses.

What Does a High or Low Result Mean?

High creatinine levels may indicate poor kidney function or damage, while very low levels could suggest muscle disorders or other health issues. Your doctor will interpret results in relation to your overall health and medical history.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure creatinine concentration using a specialized test.

What Should You Do Before the Test?

Avoid strenuous exercise or heavy meals 24 hours before the test. If you are on certain medications (like NSAIDs), inform your healthcare provider, as they may affect kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health status. Regular monitoring may be needed if you have chronic kidney disease, diabetes, or other conditions affecting kidney function.
What are the typical reference ranges?
Reference ranges vary by lab and individual factors. Your results will be compared to your baseline and clinical context rather than a single range.
Can diet affect my creatinine levels?
Dietary protein intake can influence creatinine levels, but your doctor will consider overall health and medical history when interpreting results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy