Total Serum Immunoglobulin E (IgE) Level
This test measures the amount of Immunoglobulin E (IgE), a protein in your blood linked to allergic reactions and certain immune responses.
["IgE levels help identify allergies or immune system sensitivities."]
Key facts at a glance
- LOINC
- 61217-6
- Short code
- Sw Vernal grass IgE/IgE total %
- Synonyms
- Sw Vernal grass IgE/IgE total %
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like sneezing, itching, hives, or respiratory issues that suggest allergies. It could also be used to evaluate conditions like asthma, eczema, or chronic urticaria (hives).
What to Expect Before the Test
No special preparation is needed. You may have a simple blood draw, often done in a clinic or lab. If you’re taking blood at home, ensure you follow your healthcare provider’s instructions carefully.
What the Test Results Mean
IgE levels can vary widely among individuals. High levels may indicate allergies or certain immune disorders, while low levels might suggest a weakened immune response to allergens. Results are interpreted by your doctor in the context of your symptoms and medical history.
Common Conditions Linked to IgE Testing
This test is often used to diagnose or monitor allergies (e.g., to pollen, dust mites, or foods), allergic asthma, atopic dermatitis (eczema), and other allergic conditions. It may also help assess immune-related disorders like chronic urticaria or certain parasitic infections.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: IgE plays a key role in allergic reactions by triggering the release of histamine and other chemicals that cause symptoms like swelling, itching, and inflammation. Elevated IgE levels can signal an overactive immune response to harmless substances, while low levels may indicate a reduced ability to mount an allergic reaction.
Short name
IgE Total
Frequently asked questions
What does a high IgE level mean?
What does a low IgE level mean?
Can IgE levels change over time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy