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Placental Growth Factor (PGF) with Serum/Plasma Concentration Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of placental growth factor (PGF) in your blood. PGF is a protein involved in blood vessel formation during pregnancy and may help assess early pregnancy complications.

Quick summary

["PGF levels can help monitor risks for conditions like preeclampsia or poor fetal growth."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33486-2
Short code
Symptoms 1.5h p Lac PO Patient-Imp
Synonyms
Symptoms 1.5h p Lac PO Patient-Imp
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re pregnant or at higher risk for pregnancy-related complications, such as gestational diabetes, hypertension, or other conditions affecting blood flow to the placenta. It may also be used during early pregnancy screening to evaluate placental health.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes a few minutes, and you can resume normal activities afterward. If you’re pregnant, inform your provider about any medications or supplements you’re taking.

What the Results Mean

Results are compared to reference ranges for pregnancy-specific conditions. Low or high levels may signal potential issues, such as restricted blood flow to the placenta or other pregnancy-related risks. Your provider will discuss findings with you in detail.

Common Reasons for Testing

PGF testing is often part of a broader evaluation for conditions like preeclampsia, intrauterine growth restriction (IUGR), or placental insufficiency. It may also be used in combination with other markers to assess early pregnancy viability.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Placental growth factor is a key biomarker for placental function. Elevated levels may indicate healthy placental development, while decreased levels can signal reduced blood flow or placental stress, potentially leading to complications like preeclampsia or fetal growth restrictions. Early detection helps guide interventions to improve outcomes.

Short name

PGF (Serum/Plasma)

Frequently asked questions

When might I get this test?
This test is typically ordered during early pregnancy, often between 10 and 14 weeks, but timing varies by provider. It may be part of routine prenatal care or triggered by symptoms like swelling, high blood pressure, or other pregnancy-related concerns.
What does a low or high PGF level mean?
Results aren’t interpreted alone—they’re considered with other clinical factors, such as symptoms, medical history, and additional tests. Low PGF levels may raise concerns about placental health, while high levels alone usually aren’t cause for alarm unless combined with other findings.
Do I need to fast before this test?
No fasting is required for this blood test. However, inform your provider about any medications, supplements, or recent illnesses that could affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy