Syphilis Screening Test (Qualitative)
This test checks for antibodies to the bacteria that cause syphilis, helping detect early infection or exposure.
["A simple blood test to detect syphilis infection, often used as part of routine or targeted screening."]
Key facts at a glance
- LOINC
- 39231-6
- Short code
- SYPHILISSCREENTESTSTATUS
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cphs
- CPT
- 86592
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses an immunoassay method to detect syphilis-specific antibodies in your blood. If the bacteria entered your body, your immune system produces antibodies to fight them. The test looks for these antibodies to determine if syphilis is present.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw a blood sample. The process usually takes a few minutes, and you may feel a brief pinch. If you’re pregnant, pregnant women, or have certain health conditions, your provider may recommend additional testing.
What to Expect After the Test
You can return to your normal activities immediately. There may be mild bruising or soreness at the injection site, but this typically resolves quickly. If you experience severe pain, swelling, or signs of infection (like fever or pus), contact your healthcare provider.
When You Might Need This Test
Your healthcare provider may recommend this test if you have symptoms like sores, rashes, fever, or fatigue; if you’ve had unprotected sex with multiple partners; if you’re pregnant; or if you’re part of a group at higher risk for syphilis (e.g., sexually active individuals, intravenous drug users).
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Why This Test Matters
Short name
Syphilis Screen (Qual)
Frequently asked questions
What does a positive result mean?
What does a negative result mean?
How often should I get retested?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy