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Serum or Plasma Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood using gel electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormalities in protein patterns that may indicate conditions like multiple myeloma, certain types of anemia, or other blood disorders.

Quick summary

["Electrophoresis helps detect protein imbalances that may signal serious blood conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70287-8
Short code
t(16;21)(FUS,ERG) Bld/T Ql
Synonyms
t(16;21)(FUS,ERG) Bld/T Ql
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis splits blood proteins into five main bands: albumin, alpha-1, alpha-2, beta, and gamma globulins. Each band represents different protein types, including antibodies, enzymes, and transport proteins. Abnormal band patterns can signal underlying health issues.

Why It’s Done

Doctors use this test to diagnose or monitor conditions like multiple myeloma (a cancer of plasma cells), chronic liver disease, or autoimmune disorders. It may also help evaluate symptoms like fatigue, swelling, or unexplained weight loss.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is placed on a gel for electrophoresis. The gel is placed in an electric field to separate proteins by size and charge.

Common Conditions Monitored

Abnormal results may point to conditions such as protein-losing syndromes, infections, or genetic disorders. For example, high gamma globulins could suggest multiple myeloma or other plasma cell disorders, while low albumin might indicate liver disease or malnutrition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for identifying protein abnormalities that may not be detected by routine blood tests. It helps guide treatment decisions, especially in conditions where protein patterns are key diagnostic markers. Results are interpreted by a healthcare provider based on your overall health and symptoms.

Short name

Electrophoresis Profile

Frequently asked questions

What does an electrophoresis test show?
An electrophoresis test shows the relative amounts of different proteins in your blood, separated by size and charge. It helps identify if any protein bands appear unusual, which may indicate conditions like blood cancers, liver disease, or immune disorders.
How long does it take to get electrophoresis results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before an electrophoresis test?
You may eat and drink normally before the test, as it does not require fasting. However, follow any specific instructions your healthcare provider gives you for your particular situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy