Free triiodothyronine (T3) concentration in serum/plasma
This test measures the amount of free (unbound) thyroid hormone triiodothyronine (T3) in your blood. Free T3 is the active form of thyroid hormone that your body uses.
["Free T3 helps regulate metabolism, energy levels, and other vital bodily functions."]
Key facts at a glance
- LOINC
- 14928-6
- Short code
- T3Free SerPl-sCnc
- Synonyms
- T3Free SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 80
- Ref high
- 200
- Critical range
- 20 N/A – 400 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84436
- SNOMED
- 302346007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Your doctor may order this blood test as part of a routine checkup, to help find the cause of symptoms you are having, to screen for certain health conditions, or to see how well a treatment or medication is working over time.
Your healthcare provider may order this test if you have symptoms of thyroid dysfunction, such as fatigue, weight changes, or irregular heartbeats. It may also be used to monitor thyroid hormone levels in conditions like hypothyroidism or hyperthyroidism, especially when other thyroid tests (like total T3 or T4) are needed for more precise evaluation.
Before your test, your care team will give you specific instructions, which may include fasting for a certain number of hours, drinking plenty of water, or temporarily avoiding certain medications or supplements. Tell the staff about any medicines you take, and plan to arrive a few minutes early to check in.
No special preparation is usually required, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Avoid smoking or caffeine for at least 30 minutes before your blood draw, as these can affect hormone levels.
A trained phlebotomist will wrap a band around your upper arm, clean the skin at the draw site, and insert a small needle into a vein, usually in your arm, to collect one or more small tubes of blood. The whole process usually takes only a few minutes, and you may feel a brief pinch or sting.
A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis using a specialized immunoassay method to measure free T3 levels.
Your results will be compared with established reference ranges that show what is typical for healthy adults. Values within those ranges are considered normal, while values that are higher or lower may point to a condition that needs further evaluation. Your doctor will review the findings with you and explain what they mean for your health.
Results are compared to reference ranges specific to your age, sex, and overall health. Low free T3 levels may indicate hypothyroidism, while high levels could suggest hyperthyroidism or other thyroid-related issues. Your provider will interpret results in the context of your symptoms and other tests.
Reference range
Adult: 80-200 ng/dLN/A
Take your thyroid medication after the blood draw if applicable. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Free T3
Frequently asked questions
Free T3 is important because it reflects the biologically active portion of thyroid hormone in your blood. Unlike total T3, which includes both free and protein-bound forms, free T3 is the form that directly influences metabolism and tissue function. Abnormal levels can signal thyroid disorders or other endocrine conditions that require medical attention.
Yes, you can take your usual medications, but inform your healthcare provider beforehand. Some medications, like certain thyroid replacements or stimulants, may affect thyroid hormone levels. Avoid over-the-counter supplements (e.g., multivitamins with iodine) without consulting your provider.
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results and discuss them with you.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy