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Thyroid hormone total triiodothyronine (T₃) in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of the hormone triiodothyronine (T₃) in your blood. T₃ is one of the key hormones produced by your thyroid gland that helps regulate metabolism.

Quick summary

["Your doctor may check T₃ levels to assess thyroid function and overall metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
12957-7
Short code
T3 sp6 p chal SerPl-mCnc
Synonyms
T3 sp6 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
80
Ref high
200
Critical range
20 N/A – 400 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84436
SNOMED
302346007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a total T₃ test to evaluate thyroid health, especially if you have symptoms like fatigue, weight changes, or mood swings. It can also be used alongside other thyroid tests to help diagnose conditions such as hypothyroidism or hyperthyroidism, or to monitor treatment for thyroid disorders.

What Does a Result Mean?

Results can vary based on individual health, age, and other factors. While reference ranges exist, they can differ slightly between labs. Your doctor will interpret your results in the context of your overall health and symptoms.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. You may be asked to fast for a few hours before the test, but this is not always required. The blood is sent to a lab for analysis.

Common Conditions Monitored or Diagnosed

Total T₃ levels can help diagnose or monitor conditions like thyroid dysfunction, including hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). It may also be used to check for other metabolic or endocrine issues.

Reference range

Adult: 80-200 ng/dLN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total T₃ is a critical marker for thyroid hormone status. While T₃ is less abundant than thyroxine (T₄), it plays a vital role in cellular metabolism. Abnormal levels can indicate thyroid hormone imbalances, which may require medical attention to manage symptoms or underlying conditions effectively.

Short name

Total T₃

Frequently asked questions

What causes abnormal T₃ levels?
Abnormal T₃ levels can result from thyroid disorders (such as hypothyroidism or hyperthyroidism), certain medications, or conditions affecting metabolism. Your doctor may also check for other factors like stress, diet, or underlying health issues that could influence hormone levels.
How often should I get this test?
The frequency of this test depends on your medical history, symptoms, and treatment plan. Your doctor will determine how often to repeat the test based on your individual needs, such as monitoring thyroid function during treatment or evaluating symptoms.
Can diet or lifestyle affect T₃ levels?
Yes, diet and lifestyle can influence thyroid hormone levels. Certain foods, supplements, or medications (like iodine supplements or some medications for thyroid conditions) may impact T₃. Avoiding excessive iodine intake and maintaining a balanced diet can help support normal thyroid function.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy