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Thyroid hormone total serum concentration (T₃)

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of the hormone triiodothyronine (T₃) in your blood. T₃ is a key thyroid hormone that helps regulate metabolism, energy levels, and other bodily functions.

Quick summary

["Understanding your T₃ levels can help assess thyroid function and overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
47197-9
Short code
T3 sp8 p chal SerPl-sCnc
Synonyms
T3 sp8 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
80
Ref high
200
Critical range
20 N/A – 400 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84436
SNOMED
302346007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Triiodothyronine (T₃)?

Triiodothyronine (T₃) is a hormone produced by your thyroid gland. It plays a crucial role in controlling metabolism, brain development, and maintaining normal body temperature. While thyroxine (T₄) is the primary hormone produced by the thyroid, T₃ is more biologically active and helps regulate many of the body’s functions, including heart rate, digestion, and muscle function.

Why Might You Need This Test?

Your healthcare provider may order a T₃ test to diagnose or monitor conditions related to thyroid dysfunction, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). It can also be used to evaluate symptoms like fatigue, weight changes, or unexplained heart issues.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed to measure the total concentration of T₃ in your serum. This test does not require fasting unless specified by your provider.

What Do Results Mean?

Results are interpreted in the context of your overall health and other thyroid-related tests. Abnormal levels may indicate thyroid hormone imbalances, but they are not standalone diagnoses. Your provider will discuss findings with you and may recommend additional testing or adjustments to treatment.

Reference range

Adult: 80-200 ng/dLN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Serum Triiodothyronine (T₃)

Frequently asked questions

What Are Common Causes of Abnormal Results?
Abnormal T₃ levels can result from thyroid disorders (e.g., Graves’ disease, Hashimoto’s thyroiditis), medications affecting thyroid function, or conditions like kidney disease that may alter hormone metabolism. Stress, pregnancy, or certain medications (e.g., amiodarone) can also influence T₃ levels.
How Often Should I Get This Test?
Frequency depends on your medical history and treatment plan. If you have thyroid conditions, your provider may recommend regular monitoring, such as every 3–6 months, to track changes in hormone levels.
Can I Prepare for This Test?
No special preparation is needed unless your provider instructs otherwise. Avoiding alcohol or certain medications (e.g., beta-blockers) may be advised, but always follow your provider’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy