Total Protein with Albumin Ratio (Serum)
This test measures your blood’s total protein and albumin levels to help assess protein balance and potential kidney or liver function issues.
["A ratio that reflects protein health and organ function—key for detecting conditions like kidney disease or malnutrition."]
Key facts at a glance
- LOINC
- 14015-2
- Short code
- T4 PA Bnd/Prealb SerPl
- Synonyms
- T4 PA Bnd/Prealb SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.5
- Ref high
- 12
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84436
- SNOMED
- 302345006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Your blood contains proteins like albumin and globulins, which support immunity, blood clotting, and fluid balance. This test evaluates the **total protein** (sum of all proteins) and the **albumin** (a key protein for fluid balance). The ratio helps doctors check if your kidneys or liver are working properly or if you have protein loss in urine (e.g., nephrotic syndrome).
Why Might You Need This Test?
Doctors may order this test if you have symptoms like swelling (edema), unexplained weight loss, fatigue, or signs of kidney/liver problems. It’s also used in monitoring chronic conditions like kidney disease, liver disease, or malnutrition.
How Is the Test Done?
A small blood sample is taken from your arm. The lab separates your blood into components and measures protein levels using standard lab techniques (often nephelometry or turbidimetry). Albumin is typically measured separately, and the ratio is calculated.
What Are Common Results?
Results show a **total protein** and **albumin** value, along with their ratio. While exact ranges vary by lab, a low ratio may suggest protein loss (e.g., kidney disease), while high levels could indicate dehydration or liver issues. Your doctor will interpret results in context with your health.
Reference range
Adult: 4.5-12.0 μg/dLN/A
Take your thyroid medication after the blood draw if applicable. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total Protein/Albumin Ratio
Frequently asked questions
What Causes Low Protein/Albumin Levels?
What Causes High Protein Levels?
Can I Avoid This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy