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BCG Bromocresol Green Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in plasma using bromocresol green dye to assess overall protein quality, including albumin and globulin levels. It helps identify abnormalities in protein synthesis or breakdown.

Quick summary

["This test helps evaluate protein balance in your blood, often used in monitoring conditions affecting protein metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107912-8
Short code
t(9;22)(ABL1,BCR)/control Spec-LnRto
Synonyms
t(9;22)(ABL1,BCR)/control Spec-LnRto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The BCG Bromocresol Green method uses a dye to bind to proteins in plasma. As the dye binds, it changes color, allowing for qualitative assessment of protein concentration and distribution. This includes distinguishing between albumin (the main protein in blood) and globulins (proteins involved in immunity and transport).

Clinical Use

This test is primarily used in specialized settings, such as research or rare conditions, to assess protein abnormalities that may not be captured by standard blood chemistry panels. It can help diagnose or monitor conditions like severe liver disease, kidney disease, or protein-losing syndromes.

How It’s Performed

A blood sample is drawn from a vein, typically in the arm. The plasma is separated and analyzed using electrophoresis to separate proteins based on size and charge. The BCG dye reaction is observed to determine protein distribution.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours if your doctor specifies it. Wear comfortable clothing and bring any necessary medications. Avoid heavy exercise or caffeine before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Bromocresol Green Protein Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if they suspect a condition affecting protein metabolism, such as severe liver disease (e.g., cirrhosis), kidney disease, or rare genetic disorders. It can also help monitor protein-losing conditions or evaluate protein quality in research or specialized clinical scenarios.
What are the typical results or interpretations?
Results are qualitative, meaning they describe relative protein levels rather than exact numbers. Abnormal patterns may indicate low albumin, high globulins, or other protein imbalances. Your doctor will interpret results in the context of your overall health and symptoms.
How often should this test be repeated?
Repetition depends on your condition and treatment plan. If ordered for monitoring, your doctor will determine the frequency based on your specific situation, such as whether you have a chronic disease or ongoing evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy