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Total Protein with Albumin/Globulin Ratio (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your total protein in blood and evaluates the balance between albumin and globulin proteins, which helps assess liver function, nutritional status, and potential protein-related conditions.

Quick summary

["Understanding your protein balance can help identify issues like liver disease, kidney problems, or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82904-4
Short code
t(9;22)(ABL1,BCR) Mar Ql
Synonyms
t(9;22)(ABL1,BCR) Mar Ql
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for liver disease (such as cirrhosis or hepatitis), kidney problems, malnutrition, or other conditions affecting protein production or breakdown in the body. It can also help monitor treatment responses or diagnose conditions like multiple myeloma or severe infections.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Abnormal results may indicate low or high protein levels, which could signal liver, kidney, or nutritional issues. Your doctor will discuss findings in relation to your overall health and symptoms.

Common Causes of Abnormal Results

Low protein levels might be due to liver disease, kidney failure, or poor nutrition. High protein levels could suggest dehydration, multiple myeloma, or severe infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein Ratio

Frequently asked questions

How often will I need this test?
Your doctor will determine frequency based on your health needs—some patients need it yearly, while others may require it more often if managing chronic conditions.
Can I eat or drink before this test?
Typically, fasting isn’t required, but follow your doctor’s instructions. Avoid alcohol or heavy meals 24 hours before if specified.
What if I’m pregnant or breastfeeding?
This test is generally safe during pregnancy or breastfeeding, but your doctor may adjust timing or interpretation based on your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy