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Total Bilirubin (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps the liver process waste products.

Quick summary

["Bilirubin helps identify liver function and bile flow issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75018-2
Short code
t(ABL1,BCR)e19a2 Bld/T Ql
Synonyms
t(ABL1,BCR)e19a2 Bld/T Ql
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check for liver problems, such as jaundice (yellowing of the skin and eyes), hepatitis, or blockages in the bile ducts. It can also help diagnose conditions like Gilbert’s syndrome or hemolytic anemia.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your provider know—they can help make it more comfortable.

What the Results Mean

Higher than normal levels may suggest liver disease, bile duct issues, or red blood cell breakdown. Lower levels are less commonly significant but could indicate certain genetic conditions.

Common Conditions Linked to Bilirubin Levels

Elevated bilirubin is often linked to liver or gallbladder problems, but it can also appear in conditions like infections, certain medications, or blood disorders. Always discuss your results with your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Bilirubin levels help diagnose and monitor conditions affecting the liver, bile flow, or red blood cells, guiding treatment decisions for conditions like jaundice, hepatitis, or hemolytic anemia.

Short name

Total Serum Bilirubin

Frequently asked questions

What causes bilirubin to be high in my blood?
High bilirubin can result from liver disease, bile duct blockages, or red blood cell breakdown. Other factors like certain medications or infections may also play a role.
How long does it take to get my bilirubin test results?
Results are typically available within 1–3 business days, depending on your lab. Your provider will explain them in detail during your follow-up visit.
Can I eat or drink anything before this test?
No special diet is required, but avoid alcohol or heavy meals 24 hours before testing to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy